chat loading...
Skip to Main Content

*Pharmacy Subject Guide: Clinical Guideline Resources

What are Clinical Guidelines?

Clinical guidelines are systematically developed statements that provide evidence-based recommendations for patient care in specific clinical situations. They help practitioners make consistent and appropriate decisions about medication management, diagnosis, and treatment for various diseases and conditions. Good guidelines are developed by experts and summarize large bodies of evidence to provide actionable advice. 

Key Takeaway; Clinical guidelines:

  • are evidence-based
    • will cite systematic reviews 
  • have actionable recommendations
  • contain decision-making tools 
  • are developed by experts
  • considers the harms and benefits of treatments
  • discloses bias, conflicts of interests, and grades the evidence 

Why are clinical guidelines important?

  • promotes consistency 
  • improves quality of care
  • helps with decision-making

What are some other names for clinical practice guidelines?

  • "recommendation standards"
  • "clinical guidelines"
  • "CPG"

Where to Find Clinical Guidelines

GuidelineCentral

How to find:

  • Can choose by medical specialty or by organization/society that has published the guideline
  • Search a keyword or two using the search bar

Some entries are bulleted or modular, others have links to an external site 

Con-pop up ads 

 

Trip Database

  • PICO search 
    • opt to search by entering specific populations, intervention, comparisons, and outcomes

Filter by 

  • Country
  • Content type
    • Systematic reviews
    • Guidelines
    • Evidence based synopsis 

Lists links to external websites 

Cons- doesn't produce all guidelines available, guidelines may be limited or old 

 

ECRI Guidelines Trust

Search a condition or a different keyword or two

Filter by 

  • Year
  • Organization (that published guideline)
  • Demographic
  • Clinical Area
  • Intervention
  • Show Guidelines 
    • Systematic review conducted
    • Quality of evidence rated 
    • Strength of recommendations rated 

UpToDate

How to find:

  • search specific conditions and interventions
  • can modify search to display specific demographics
  • once you select your content from the search results, a modular outline will come up
  • look for "Society Guideline Links" in outlines: these are links to external websites containing the guidelines

 

The United States Preventive Services Task Force

The USPSTF’s scope is to “make recommendations on clinical preventive services to primary care clinicians,” including screening tests, behavioral counseling, and preventive medications. The USPSTF recommendations only address services offered in primary care settings.

Search by:

  • keyword
    • condition
    • population
    • intervention

Filter results by:

  • age
  • weight
  • height
  • sex
  • pregnant
  • tobacco user 
  • sexually active 

Pharmacist Letter:

  • Provides charts and tables related to various treatments/conditions
  • Search by entering one or two keywords in the main search bar or browsing the website. 

The AHRQ

The Agency for Healthcare Research and Quality is the agency in charge of improving the quality and safety. Their website "Guidelines and Measures" will search within all AHRQ sites and provide some access to guidelines. 

Con: cannot filter by year or anything else

 

National Center for Complementary and Integrative Health: Clinical Practice Guidelines

Issued by third-party organizations, and not NCCIH, these guidelines define the role of specific diagnostic and treatment modalities in the diagnosis and management of patients. The statements contain recommendations that are based on evidence from a rigorous systematic review and synthesis of the published medical literature.

This is a list of resources grouped by subject matter. Click the links to access external websites containing guidelines. 

Guidelines are published by a number of entities, the most trustworthy of which are educational institutions, medical institutions, and health organizations. You can search for clinical practice guidelines using a simple google search.

To search for .edu, .org, or .gov specific websites

  1. enter the search terms you want to look for.
  2. after your search terms,
    • type site:.edu to yield only websites that end in .edu
    • type site:.org to yield only websites that end in .org
    • type site:.gov to yield only websites that end in .gov

Example: clinical guidelines for geriatric patients with diabetes site:.org 

Evaluating Clinical Guidelines

Frequently Used Terminology

Therapeutic Research Center: Clinical Resource #36116

Class of Recommendation and Level of Evidence

ACC/AHA Recommendation System: Applying Class of Recommendation and Level of Evidence to Clinical Strategies, Interventions, Treatments, or Diagnostic Testing in Patient Care. Use this table to determine what different levels of Class of Recommendations and Level of Evidence mean. Cick the image to enlarge.